Empowering Life Sciences with Innovative Purification Solutions

Purivise delivers ready-to-use, advanced single-use resins.
We turn challenges in biopharmaceutical manufacturing into opportunities for growth. By advancing resin technology and optimizing cGMP workflows, we provide reliable, high-quality solutions that enhance efficiency, ensure consistency, and support your innovation journey.

Proven Purification Technology

Purivise supplies and develops Innovative Resin Technology for Biopharmaceutical Purification. Our core product is PuriZorb-PG4, a sterile, endotoxin-free, purified and activated Amberlite® XAD-4 resin suspension supplied in 2L polycarbonate bottles, ready-to-use in PBS buffer. Unlike dry-packaged adsorbents or column cartridges, PuriZorb-PG4 requires no equilibration or washing steps prior to use. Simply add it directly to the protein, vaccine, or biomolecule solution to rapidly remove detergents and hydrophobic impurities.

Produced under cGMP conditions, PuriZorb-PG4 guarantees consistency, sterility, and reproducibility across scales. It is ideally suited for sensitive biopharmaceutical workflows, where detergent removal is a critical step for maintaining product functionality and regulatory compliance.

Amberlite® XAD-4 resin is a well-established, macroreticular, crosslinked polystyrene-divinylbenzene adsorbent. Its high surface area (~750 m²/g) and pore structure (~40 Å mean pore diameter) provide efficient adsorption of small hydrophobic molecules and detergents from aqueous solutions. The resin is chemically inert, autoclavable, and exhibits negligible protein binding, ensuring that valuable biomolecules remain intact during purification. The bio-beads are often used in biotechnological process.

Amberlite® XAD-4 is a trademark of DuPont de Nemours, Inc.

PuriZorb-PG4 is a versatile resin that delivers reliable performance across numerous biopharmaceutical purification processes…

Simply add it directly to the protein, vaccine, or biomolecule solution to rapidly remove detergents and hydrophobic impurities.

Vaccine Production

Removal of detergents such as Triton X-100, SDS, CTAB, and Sarkosyl after viral inactivation or protein solubilization.

Protein Purification

Refolding of membrane proteins and inclusion body-derived proteins with complete detergent removal, demonstrated in COVID-19 subunit vaccine candidates.

Liposome and virosome reconstitution

Removal of detergents used to solubilize phospholipids, enabling functional vesicle formation. Facilitates detergent-mediated reconstitution of lipid-based carriers, providing a reliable method for producing functional liposomes and virosomes.

Endotoxines and impurities clearance

Adsorption of hydrophobic impurities, phenols, pesticides, and small molecules from pharmaceutical and food preparations.

Innovations in cGMP manufacturing processes for life sciences

Discover our advanced technologies and expertise.

Biotechnological Purification

Optimizing purification processes for maximum effectiveness.

Process development

Development of efficient and scalable production processes.

Consultancy

Customized advice for cGMP compliance and innovation.

Quality control

Careful monitoring to ensure the highest product standards.

Innovative solutions for cGMP production processes

Discover our expertise in biotechnological purification technologies with a focus on quality and innovation.

cGMP Process Optimization

Optimized production processes tailored to the life sciences sector.

Biotechnological Purification

Precision purification methods for high-quality bioproducts.

Consultancy & Support

Advice and guidance for the implementation of innovative technologies.

Trusted by leading experts

Our certifications and rave customer reviews confirm our commitment to the highest standards within the life sciences sector, with a focus on innovative cGMP production and biotechnological purification.

Certified to cGMP standards

Ecovadis assessment of the Manufacturing Site

Get in Touch with us Today

Partner with us to enhance your biopharmaceutical purification workflows. Our team is ready to provide expert guidance, tailored solutions, and innovative products like PuriZorb-PG4 to support your success. Connect with us today and discover how Purivise can empower your next breakthrough.

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